研究開発・学会発表
診療・治療
Fertility and Sterility
- A healthy birth after intracytoplasmic sperm injection using ejaculated spermatozoa from a patient with Kartagener’s syndrome
- Vol. 93, No.6, April 2010
- Fertility and Sterility
- Yukiko Matsumoto a, Sakae Goto a, Hiromi Hashimoto a, Shoji Kokeguchi a,
Masahide Shiotani a,Hiroshi Okada b
a Hanabusa Women’s Clinic, Kobe, Japan
b Dokkyo Medical University Koshigaya Hospital, Koshigaya, Japan
Objective: To report a healthy birth that was achieved by intracytoplasmic sperm injection (ICSI) using ejaculated spermatozoa from a patient with Kartagener’s syndrome.
Design: Case report
Setting: Private infertility clinic
Patient(s): Couple with male factor infertility due to Kartagener’s syndrome
Intervention(s): Intracytoplasmic sperm injection with ejaculated sperm
Main outcome measure(s): Semen characteristics, sperm motility, fertilization, pregnancy, and birth after ICSI.
Result(s): With ejaculated sperm, the fertilization rate were 73% in the first stimulation cycle and 100% in the second cycle. Intracytoplasmic sperm injection was successful. The pregnancy resulted in birth of a single healthy child.
Conclusions: With ejaculated sperm, successful pregnancy after ICSI in couples with Kartagener’s syndrome is possible. Kartagener’s syndrome is a heterogeneous group of disorders with similar clinical presentations, and treatment should be individualized depending on sperm motility.
Key Words: Kartagener’s syndrome, ICSI, ejaculated sperm
